Avastin is the trade name for the drug bevacizumab. It belongs to a group of drugs called monoclonal antibodies
Many diseases of the eye, such as age-related macular degeneration (ARMD) and diabetic retinopathy, damage the retina and cause blindness when blood vessels around the retina grow abnormally and leak fluid, causing the layers of the retina to separate. This abnormal growth is caused by VEGF (Vascular endothelial growth factor), so bevacizumab has been successfully used to inhibit VEGF and slow this growth.
How Does Avastin Work?
New Abnormal blood vessels need a body chemical called Vascular endothelial growth factor(VEGF) to grow. Avastin blocks VEGF, slowing the growth of blood vessels in the eye. Drugs that block the trouble-causing VEGF are called anti-VEGF drugs.
Common Indication of Avastin in Eye
Avastin is used to treat following eye diseases.
Severe Diabetic Retinopathy
Retinal Vein Occlusion
What Happens During Treatment with Avastin?
It is given intravitreously (Into the vitreous humour of the eye)
Before the procedure, your ophthalmologist will clean your eye to prevent infection and numb your eye with medicine. A very thin needle is passed through the white part of your eye and the drug is injected. Usually you do not see the needle itself. You may need to continue having these injections over many months.
Sometime ophthalmologists will combine Avastin treatment with other treatments for the best chance of saving your vision.
Avastin side effects (Most Common)
Red, irritated eye
Small specks or bubble shapes in vision
Elevation in eye pressure
Rare Avastin complications
Inflammation inside the eye
Retina or vitreous bleeding
A decrease in eye pressure
Intraocular infection (endophthalmitis)
The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.
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