A comparison of the efficacy and tolerability of olopatadine hydrochloride 0.1% ophthalmic solution and cromolyn sodium 2% ophthalmic solution in seasonal allergic conjunctivitis has found that Six weeks’ installation of olopatadine 0.1% ophthalmic solution two times a day had a significantly greater effect on the ocular signs and symptoms of allergic conjunctivitis compared with 6 weeks’ installation of cromolyn 2% (sodium Cromoglycate) ophthalmic solution 4 times a day dose. Both treatments were well tolerated by patients in all age groups; however, olopatadine appeared to have better local tolerability in children aged <11 years.
Uses of Olopatadine and cromolyn sodium eye drops
Treatments for allergic conjunctivitis have various mechanisms of action. Cromolyn sodium stabilizes conjunctival mast cells by preventing calcium influx across the cell membrane, whereas olopatadine hydrochloride is both an antihistamine and a mast cell stabilizer
List of Commonly Available Olopatadine Eye Drops in Nepal
1. Rapidon Eye Drop
Manufactured By: Micro Labs Limited, India
MRP: NRS 163.2 (IC 102.00)
2. Winolap Eye Drop
Manufactured By: Sun Pharmaceutical Medicare Limited, India
MRP: NRS 193.6 (IC 121.00)
3. OPD-1 Eye Drop
Manufactured By: Sumy Pharmaceuticals (P) Ltd, Nepal
MRP: NRS 165.00
Available Olopatadine eye drops in the USA
Pataday eye drops come in two packages one contains olopatadine 0.1% -the-counter (OTC) Alcon Pataday Twice Daily Relief 5ml and another is olopatadine 0.2% by Alcon come under the name Pataday Once Daily Relief 2.5ml eye drops.
Pataday is currently only available for over-the-counter sale in the United States of America.
List of Commonly Available Sodium Cromoglycate Eye Drops in Nepal and India
Aurocrome Eye Drops
Manufactured By: AUROLAB PVT LTD
Contains: Sodium Cromoglycate